P&S Nano are a local topical patch business who has collaborated with the centre for Nanohealth at Swansea University to develop a topical treatment for Psoriasis. Psoriasis is a common chronic skin disorder that causes red and flaky patches of skin. The disease affects around 2% of people in the UK. Current treatments for mild to moderate psoriasis consist of topical creams or ointment formulations containing Vitamin D analogues or topical orticosteroids. There can be problems with these treatments such as skin irritation and blemishing of garments.
P&S Nano and Swansea researchers have developed a hydrogel patch containing drug-loaded micro-spheres for the treatment of mild to moderate psoriasis. The technology centres on a technique to defuse oil-based dithranol into dried form and then infusing this into a hydrogel using a polymer which as acts as a carrier for the drug microparticles. With this technology the microspheres have a 99% drug encapsulation rate. The gel enriched patch is applied directly to the psoriasis site and worn for 4-6 hours. P&S Nano Ltd have licenced this technology for the treatment psoriasis and other topical drug patches including microspheres.
As well as individuals affected with mild to moderate psoriasis this technology would have applications for other dermatological conditions such as eczema, lichen planus and other inflammatory skin conditions.
A UK patent application for a topical drug patch containing microspheres has been devised (GB1314909.1) Swansea is seeking companies wishing to license this technology or collaborate in co-development.